If the “Save”-button on map or marker edit pages is disabled and cannot be clicked, it is likely that this is caused by a plugin conflict. To verify this, please disable all other plugins but Maps Marker Pro and try again.
If this does not help, it is likely that there might be an issue with your general WordPress AJAX endpoint. Have a look into the browser console (can be opened with key F11 for example) to see if there are any error messages. Send us these error messages in a support ticket so that we can have a closer look.